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BBS4 抗体 (N-Term)

This anti-BBS4 antibody is a 兔 多克隆 antibody detecting BBS4 in WB 和 IHC (p). Suitable for 人.
产品编号 ABIN7466958
发货至: 中国

Quick Overview for BBS4 抗体 (N-Term) (ABIN7466958)

抗原

See all BBS4 抗体
BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

适用

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宿主

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克隆类型

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多克隆

标记

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This BBS4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    交叉反应

    小鼠, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human BBS4. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Neuro2A , C8D30 , NIH-3T3

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.04 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    BBS4 (Bardet-Biedl Syndrome 4 (BBS4))

    别名

    Bardet-Biedl syndrome 4

    背景

    Bardet-Biedl syndrome 4,This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.

    分子量

    58 kDa

    基因ID

    585

    UniProt

    Q96RK4

    途径

    Hedgehog Signaling, Tube Formation, Maintenance of Protein Location
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