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STIM1 抗体 (C-Term)

This anti-STIM1 antibody is a 兔 多克隆 antibody detecting STIM1 in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7466938
发货至: 中国

Quick Overview for STIM1 抗体 (C-Term) (ABIN7466938)

抗原

See all STIM1 抗体
STIM1 (Stromal Interaction Molecule 1 (STIM1))

适用

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宿主

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克隆类型

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多克隆

标记

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This STIM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    C-Term

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human STIM1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: mouse thymus

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.79 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    STIM1 (Stromal Interaction Molecule 1 (STIM1))

    别名

    stromal interaction molecule 1

    背景

    Stromal interaction molecule 1 , D11S4896E , GOK , IMD10 , STRMK , TAM , TAM1,This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.

    分子量

    77 kDa

    基因ID

    6786

    UniProt

    Q13586

    途径

    TCR Signaling, BCR Signaling
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