Sortilin 1 抗体
Quick Overview for Sortilin 1 抗体 (ABIN7466714)
抗原
See all Sortilin 1 (SORT1) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Sortilin 1. The exact sequence is proprietary.
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亚型
- IgG
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anti-Sortilin 1 (SORT1) (AA 203-299) antibody
SORT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Sortilin 1 (SORT1) (AA 520-760) antibodySORT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 328-457) antibodySORT1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 320-335), (Extracellular) antibodyKO Validated SORT1 适用: 人 WB, IHC, FACS, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 731-831) antibodySORT1 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 50-320) antibodySORT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) (AA 203-299) antibodySORT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sortilin 1 (SORT1) antibodyKD Validated SORT1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Sortilin 1 (SORT1) (AA 320-335), (Extracellular) antibody (FITC)SORT1 适用: 人 FACS 宿主: 兔 Polyclonal FITC
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Mouse brain
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Sortilin 1 (SORT1)
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别名
- sortilin 1
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背景
- Sortilin 1 , Gp95 , LDLCQ6 , NT3 , NTR3,This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq]
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分子量
- 92 kDa
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基因ID
- 6272
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UniProt
- Q99523
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途径
- Neurotrophin Signaling Pathway
抗原
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