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MRVI1 抗体 (C-Term)

The 兔 多克隆 anti-MRVI1 antibody is suitable to detect MRVI1 in samples from 人. It has been validated for WB 和 IHC (p).
产品编号 ABIN7466656
发货至: 中国
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Quick Overview for MRVI1 抗体 (C-Term) (ABIN7466656)

抗原

See all MRVI1 抗体
MRVI1 (Murine Retrovirus Integration Site 1 Homolog (MRVI1))

适用

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宿主

  • 3

克隆类型

  • 3
多克隆

标记

  • 3
This MRVI1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 1
    • 1
    C-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human MRVI1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: MCF-7

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    MRVI1 (Murine Retrovirus Integration Site 1 Homolog (MRVI1))

    别名

    murine retrovirus integration site 1 homolog

    背景

    Murine retrovirus integration site 1 homolog , IRAG , JAW1L,This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is downregulated during lymphoid differentiation. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, few of which initiate translation at a non-AUG (CUG) start site. [provided by RefSeq]

    分子量

    96 kDa

    基因ID

    10335

    UniProt

    Q9Y6F6
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