EP400 抗体
Quick Overview for EP400 抗体 (ABIN7466625)
抗原
See all EP400 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human p400. The exact sequence is proprietary.
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亚型
- IgG
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anti-E1A Binding Protein P400 (EP400) (AA 743-850) antibody
EP400 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-E1A Binding Protein P400 (EP400) (AA 1-985) antibodyEP400 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-E1A Binding Protein P400 (EP400) (AA 90-330) antibodyEP400 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: MCF-7
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.95 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- EP400 (E1A Binding Protein P400 (EP400))
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别名
- E1A binding protein p400
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背景
- E1A binding protein p400 , CAGH32 , P400 , TNRC12,Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity.
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分子量
- 343 kDa
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基因ID
- 57634
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UniProt
- Q96L91
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途径
- Chromatin Binding
抗原
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