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EP400 抗体 (AA 1051-1250)

EP400 适用: 人 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386134
发货至: 中国
  • 抗原 See all EP400 抗体
    EP400 (E1A Binding Protein P400 (EP400))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1051-1250
    适用
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 5
    • 4
    克隆类型
    • 7
    • 2
    多克隆
    标记
    • 9
    This EP400 antibody is un-conjugated
    应用范围
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human p400
    亚型
    IgG
    Top Product
    Discover our top product EP400 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    EP400 (E1A Binding Protein P400 (EP400))
    别名
    P400 (EP400 产品)
    别名
    CAGH32 antibody, P400 antibody, TNRC12 antibody, 1700020J09Rik antibody, AU023439 antibody, mDomino antibody, mKIAA1498 antibody, p400 antibody, E1A binding protein p400 antibody, EP400 N-terminal-like protein antibody, helicase domino antibody, E1a binding protein P400 antibody, EP400 antibody, Ep400 antibody, LOC738562 antibody, LOC5570719 antibody, CpipJ_CPIJ007689 antibody, CpipJ_CPIJ007688 antibody, CpipJ_CPIJ007686 antibody, CpipJ_CPIJ008061 antibody
    背景

    Synonyms: CAG repeat protein 32, CAGH32, DKFZP434I225, Domino homolog, E1A binding protein p400, EP 400, EP400, FLJ42018, FLJ45115, hDomino, KIAA1498, KIAA1818, p400 kDa SWI2/SNF2 related protein, P400 SWI2/SNF2-related protein, TNRC12, Trinucleotide repeat containing 12, Trinucleotide repeat containing gene 12 protein, EP400_HUMAN.

    Background: NuAR is a multi-protein histone acetyltransferase complex that functions to acetylate the nucleosomal Histones H4 and H2A, thereby activating transcription of select target genes. p400, also known as EP400 (E1A binding protein p400) or mDomino, localizes to the nucleus and is a component of the NuAR complex. Expressed in brain, liver, thymus, lung, spleen, colon and kidney, p400 regulates the transcriptional activity of proteins such as MZF-1 and contributes to the ATPase and helicase activities of NuA4. p400 is a SWI2/ SNF2-related protein that can interact with the adenovirus oncoprotein E1A, thus activating the proapoptotic activity of E1A. The ability of p400 to regulate transcriptional and apoptotic activity suggests that the NuAR complex may be a crucial component of cell proliferation, transformation and, possibly, carcinogenesis. Five isoforms of p400 exist due to alternative splicing events.

    基因ID
    57634
    途径
    Chromatin Binding
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