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Dynamitin 抗体

This 兔 多克隆 antibody specifically detects Dynamitin in WB, IF, IHC (p) 和 ICC. It exhibits reactivity toward 人.
产品编号 ABIN7466610
发货至: 中国
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Quick Overview for Dynamitin 抗体 (ABIN7466610)

抗原

See all Dynamitin (DCTN2) 抗体
Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Dynamitin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human DCTN2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: MCF-7

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

    别名

    dynactin subunit 2

    背景

    Dynactin subunit 2 , DCTN50 , DYNAMITIN , HEL-S-77 , RBP50,This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq]

    分子量

    44 kDa

    基因ID

    10540

    UniProt

    Q13561

    途径

    M Phase, Ribonucleoprotein Complex Subunit Organization
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