NCF4 抗体
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北京 101111
Quick Overview for NCF4 抗体 (ABIN7466484)
抗原
See all NCF4 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Full length human NCF4 Recombinant protein.
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亚型
- IgG
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anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 111-339) antibody
NCF4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) antibodyNCF4 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (Internal Region) antibodyVerified NCF4 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-190) antibodyNCF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (C-Term) antibodyNCF4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 136-239) antibodyNCF4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) antibodyNCF4 适用: 人 WB, ICC 宿主: 兔 Monoclonal 24GB45 unconjugated Recombinant Antibody
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-339) antibodyNCF4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-339) antibodyNCF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 260-289), (C-Term) antibodyNCF4 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18508 unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat , Raji , K562 , THP-1
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.87 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
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别名
- neutrophil cytosolic factor 4
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背景
- Neutrophil cytosolic factor 4 , CGD3 , NCF , P40PHOX , SH3PXD4,The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
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分子量
- 39 kDa
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基因ID
- 4689
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UniProt
- Q15080
抗原
-
