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COL11A2 抗体 (N-Term)

The 小鼠 单克隆 anti-COL11A2 antibody is suitable to detect COL11A2 in samples from 人. It has been validated for WB.
产品编号 ABIN7466206
发货至: 中国
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Quick Overview for COL11A2 抗体 (N-Term) (ABIN7466206)

抗原

See all COL11A2 抗体
COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

适用

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宿主

  • 37
  • 3
  • 1
小鼠

克隆类型

  • 39
  • 2
单克隆

标记

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This COL11A2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

GT6410
  • 抗原表位

    • 15
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    • 1
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    • 1
    • 1
    • 1
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    N-Term

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human COL11A2. The exact sequence is proprietary.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: human COL11A2-transfected 293T cells (N-terminal fragment of COL11A2 isoform 1) , mouse brain , rat brain

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

    别名

    collagen type XI alpha 2 chain

    背景

    Collagen type XI alpha 2 chain , DFNA13 , DFNB53 , FBCG2 , HKE5 , OSMEDA , OSMEDB , PARP , STL3,This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Three transcript variants encoding different isoforms have been identified for this gene. A pseudogene is located nearby on chromosome 6. [provided by RefSeq]

    分子量

    172 kDa

    基因ID

    1302

    UniProt

    P13942

    途径

    RTK signaling, Sensory Perception of Sound, Chromatin Binding
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