COL11A2 抗体 (N-Term)
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北京 101111
Quick Overview for COL11A2 抗体 (N-Term) (ABIN7466206)
抗原
See all COL11A2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Affinity purified by Protein G.
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免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human COL11A2. The exact sequence is proprietary.
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亚型
- IgG1
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: human COL11A2-transfected 293T cells (N-terminal fragment of COL11A2 isoform 1) , mouse brain , rat brain
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))
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别名
- collagen type XI alpha 2 chain
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背景
- Collagen type XI alpha 2 chain , DFNA13 , DFNB53 , FBCG2 , HKE5 , OSMEDA , OSMEDB , PARP , STL3,This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Three transcript variants encoding different isoforms have been identified for this gene. A pseudogene is located nearby on chromosome 6. [provided by RefSeq]
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分子量
- 172 kDa
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基因ID
- 1302
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UniProt
- P13942
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途径
- RTK signaling, Sensory Perception of Sound, Chromatin Binding
抗原
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