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TREX1 抗体

The 兔 多克隆 anti-TREX1 antibody (ABIN7466063) specifically detects TREX1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7466063
发货至: 中国
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Quick Overview for TREX1 抗体 (ABIN7466063)

抗原

See all TREX1 抗体
TREX1 (three Prime Repair Exonuclease 1 (TREX1))

适用

  • 49
  • 6
  • 5

宿主

  • 43
  • 7

克隆类型

  • 27
  • 23
多克隆

标记

  • 26
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
This TREX1 antibody is un-conjugated

应用范围

  • 34
  • 18
  • 17
  • 13
  • 10
  • 6
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human TREX1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.75 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TREX1 (three Prime Repair Exonuclease 1 (TREX1))

    别名

    three prime repair exonuclease 1

    背景

    Three prime repair exonuclease 1 , AGS1 , CRV , DRN3 , HERNS,This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

    分子量

    39 kDa

    基因ID

    11277

    UniProt

    Q9NSU2

    途径

    Apoptosis
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