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GRB10 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects GRB10 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7465917
发货至: 中国
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Quick Overview for GRB10 抗体 (N-Term) (ABIN7465917)

抗原

See all GRB10 抗体
GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

适用

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宿主

  • 47
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克隆类型

  • 50
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多克隆

标记

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This GRB10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
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    N-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human GRB10. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HeLa

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

    别名

    growth factor receptor bound protein 10

    背景

    Growth factor receptor bound protein 10 , GRB-IR , Grb-10 , IRBP , MEG1 , RSS,The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

    分子量

    67 kDa

    基因ID

    2887

    UniProt

    Q13322

    途径

    Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
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