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MLH3 抗体 (N-Term)

The 兔 多克隆 anti-MLH3 antibody is suitable to detect MLH3 in samples from 人. It has been validated for WB.
产品编号 ABIN7465777
发货至: 中国
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Quick Overview for MLH3 抗体 (N-Term) (ABIN7465777)

抗原

See all MLH3 抗体
MLH3 (MutL Homolog 3 (MLH3))

适用

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宿主

  • 14
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克隆类型

  • 15
多克隆

标记

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This MLH3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 2
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    N-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human MLH3. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HCT116

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.54 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    MLH3 (MutL Homolog 3 (MLH3))

    别名

    mutL homolog 3

    背景

    MutL homolog 3 , HNPCC7,This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq]

    分子量

    164 kDa

    基因ID

    27030

    UniProt

    Q9UHC1

    途径

    Chromatin Binding
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