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DNMT3B 抗体 (C-Term)

This anti-DNMT3B antibody is a 兔 多克隆 antibody detecting DNMT3B in WB. Suitable for 小鼠.
产品编号 ABIN7465665
发货至: 中国

Quick Overview for DNMT3B 抗体 (C-Term) (ABIN7465665)

抗原

See all DNMT3B 抗体
DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

适用

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小鼠

宿主

  • 92
  • 7
  • 2
  • 1

克隆类型

  • 85
  • 17
多克隆

标记

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This DNMT3B antibody is un-conjugated

应用范围

  • 83
  • 40
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Western Blotting (WB)
  • 抗原表位

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    C-Term

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of mouse DNMT3B. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: DNMT3B transfected 293T

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

    别名

    DNA methyltransferase 3B

    背景

    DNA methyltransferase 3B , MmuIIIB,Required for genome wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing. In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9.

    分子量

    97 kDa

    基因ID

    13436

    UniProt

    O88509
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