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E2F6 抗体

This anti-E2F6 antibody is a 兔 多克隆 antibody detecting E2F6 in WB, IF, ICC 和 IHC (p). Suitable for 人.
产品编号 ABIN7465512
发货至: 中国

Quick Overview for E2F6 抗体 (ABIN7465512)

抗原

See all E2F6 抗体
E2F6 (E2F Transcription Factor 6 (E2F6))

适用

  • 33
  • 17
  • 12
  • 6
  • 5
  • 5
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  • 3
  • 1
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宿主

  • 25
  • 7
  • 1

克隆类型

  • 24
  • 9
多克隆

标记

  • 33
This E2F6 antibody is un-conjugated

应用范围

  • 30
  • 12
  • 11
  • 9
  • 5
  • 4
  • 4
  • 3
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  • 1
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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human E2F6. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: A549

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    E2F6 (E2F Transcription Factor 6 (E2F6))

    别名

    E2F transcription factor 6

    背景

    E2F transcription factor 6 , E2F-6,This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms. [provided by RefSeq]

    分子量

    32 kDa

    基因ID

    1876

    UniProt

    O75461
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