Cullin 4B 抗体
Quick Overview for Cullin 4B 抗体 (ABIN7465207)
抗原
See all Cullin 4B (CUL4B) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
 - 人, 小鼠, 大鼠
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纯化方法
 - Purified by antigen-affinity chromatography.
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免疫原
 - Recombinant protein encompassing a sequence within the center region of human Cullin 4b. The exact sequence is proprietary.
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亚型
 - IgG
 
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应用备注
 - WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293T , A431 , HeLa , HepG2 , A375 , Neuro2A , C8D30 , NIH-3T3 , Raw 264.7 , C2Cl2 , PC-12 , Rat2
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 mg/mL
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缓冲液
 - 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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- Cullin 4B (CUL4B)
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别名
 - cullin 4B
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背景
 - Cullin 4B , CUL-4B , MRXHF2 , MRXS15 , MRXSC , SFM2,This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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分子量
 - 104 kDa
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基因ID
 - 8450
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UniProt
 - Q13620
 
抗原
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