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- 抗原 See all Cullin 4B (CUL4B) 抗体
- Cullin 4B (CUL4B)
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抗原表位
- AA 1-200
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cullin 4B antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Cullin-4B protein (1-200AA)
- 亚型
- IgG
- Top Product
- Discover our top product CUL4B Primary Antibody
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anti-Cullin 4B (CUL4B) (Internal Region) antibody
CUL4B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4B (CUL4B) (AA 1-300) antibodyCUL4B 适用: 人, 小鼠, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Cullin 4B (CUL4B) (AA 1-200) antibodyCUL4B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4B (CUL4B) (AA 9-152) antibodyCUL4B 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4B (CUL4B) (AA 1-913) antibodyCUL4B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin 4B (CUL4B) antibodyCUL4B 适用: 人, 大鼠, 斑马鱼 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4B (CUL4B) antibodyCUL4B 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4B (CUL4B) antibodyCUL4B 适用: 人, 大鼠, 斑马鱼, 鱼 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cullin 4B (CUL4B) (AA 1-300) antibodyCUL4B 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 小鼠 Monoclonal 7F8 unconjugated
anti-Cullin 4B (CUL4B) (AA 250-278) antibodyCUL4B 适用: 人 WB 宿主: 兔 Polyclonal RB42521 unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Cullin 4B (CUL4B)
- 别名
- CUL4B (CUL4B 产品)
- 别名
- MRXHF2 antibody, MRXS15 antibody, MRXSC antibody, SFM2 antibody, 2700050M05Rik antibody, AA409770 antibody, CUL-4B antibody, mKIAA0695 antibody, RGD1564494 antibody, im:7140950 antibody, im:7150765 antibody, MGC115611 antibody, Tb03.1J15.620 antibody, sfm2 antibody, mrxsc antibody, mrxhf2 antibody, cullin 4B antibody, cullin 4B S homeolog antibody, CUL4B antibody, Cul4b antibody, cul4b antibody, cul4b.S antibody, Tb927.3.1290 antibody
- 背景
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Background: Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced DNA damage. Targeted to UV damaged chromatin by DDB2 and may be important for DNA repair and DNA replication. Required for ubiquitination of cyclin E, and consequently, normal G1 cell cycle progression. Regulates the mammalian target-of-rapamycin (mTOR) pathway involved in control of cell growth, size and metabolism. Specific CUL4B regulation of the mTORC1-mediated pathway is dependent upon 26S proteasome function and requires interaction between CUL4B and MLST8.
Aliases: CUL 4B antibody, CUL-4B antibody, CUL4B antibody, CUL4B_HUMAN antibody, Cullin-4B antibody, DKFZp686F1470 antibody, KIAA0695 antibody, MRXHF2 antibody, MRXSC antibody, SFM2 antibody
- UniProt
- Q13620
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