COPS5 抗体
Quick Overview for COPS5 抗体 (ABIN7464988)
抗原
See all COPS5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠
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纯化方法
- Protein G purified
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免疫原
- The full-length mouse JAB-1 gene expressed in E. coli.
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亚型
- IgG2a
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应用备注
- WB: 0.5 - 1 μg/mL. IP: 0.5 - 1 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: 293 cell lysate
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
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别名
- COP9 signalosome subunit 5
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背景
- COP9 signalosome subunit 5 , CSN5 , JAB1 , MOV-34 , SGN5,The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
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分子量
- 38 kDa
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基因ID
- 10987
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UniProt
- Q92905
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途径
- Cell Division Cycle
抗原
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