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CBS 抗体

The 小鼠 单克隆 anti-CBS antibody (Clone GT519) (ABIN7464920) specifically detects CBS in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7464920
发货至: 中国
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Quick Overview for CBS 抗体 (ABIN7464920)

抗原

See all CBS 抗体
CBS (Cystathionine-beta-Synthase (CBS))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CBS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated

克隆位点

GT519
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human CBS. The exact sequence is proprietary.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: rat liver , Raji , K562 , mouse liver , 293T , HeLa , CBS-transfected 293T

    Validation: KO/KD, Overexpression

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.97 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    CBS (Cystathionine-beta-Synthase (CBS))

    别名

    cystathionine-beta-synthase

    背景

    Cystathionine-beta-synthase , CBSL , HIP4,The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeq]

    分子量

    61 kDa

    基因ID

    875

    UniProt

    P35520, P0DN79
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