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CBS 抗体 (N-Term)

Name: CBS 抗体 (N-Term)
SKU: ABIN2782348
Availability: OutOfStock

CBS 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

IHC

Image no. 2 for anti-Cystathionine-beta-Synthase (CBS) (N-Term) antibody (ABIN2782348)

Immunohistochemistry (IHC) image for anti-Cystathionine-beta-Synthase (CBS) (N-Term) antibody (ABIN2782348)

IHC

WB Suggested Anti-CBS Antibody Titration: 1.

Host: Rabbit Target Name: CBS Sample Tissue: Rat Liver Antibody Dilution: 1ug/ml

Host: Rabbit Target Name: CBS Sample Type: HepG2 Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/lane Gel Concentration: 0.

IHC

8 images

(8 references)

产品编号 ABIN2782348

发货至: 中国

Datasheet as PDF

抗原 See all CBS 抗体

CBS (Cystathionine-beta-Synthase (CBS))
抗原表位
15

9

6

6

4

4

2

2

2

1

1

1

1

1

1

1

1
N-Term
适用
51

39

10

2

1

1

1

1

1

1

1
人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马, Saccharomyces cerevisiae, 斑马鱼
宿主
62

9
兔
Compatible Secondaries
克隆类型
58

13
多克隆
标记
36

6

6

4

2

2

2

2

2

2

1

1

1

1

1

1

1
This CBS antibody is un-conjugated
应用范围
53

31

14

14

14

13

13

7

6

5

3

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

RCIIVMPEKM SSEKVDVLRA LGAEIVRTPT NARFDSPESH VGVAWRLKNE

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against CBS. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human CBS

Top Product

Discover our top product CBS Primary Antibody
anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS 适用: 人 WB, ELISA, IHC (p), IP, RNAi 宿主: 小鼠 Monoclonal 3E1 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 252-551) antibody
CBS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 104-133), (N-Term) antibody
CBS 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB22961 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6A9 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-413) antibody
CBS 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) antibody
KO Validated CBS 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 301-330) antibody
CBS 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB21183 unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-551) antibody
CBS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Cystathionine-beta-Synthase (CBS) (AA 1-100) antibody
CBS 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3D10 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 551 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Yamane, Kanno, Nakamura, Fujino, Murayama: "Hydrogen sulfide-mediated regulation of contractility in the mouse ileum with electrical stimulation: roles of L-cysteine, cystathionine β-synthase, and K+ channels." in: European journal of pharmacology, Vol. 740, pp. 112-20, (2014) (PubMed).

Geillinger, Rathmann, Köhrle, Fiamoncini, Daniel, Kipp: "Hepatic metabolite profiles in mice with a suboptimal selenium status." in: The Journal of nutritional biochemistry, Vol. 25, Issue 9, pp. 914-22, (2014) (PubMed).

Porteus, Abdallah, Pollack, Kumai, Kwong, Yew, Milsom, Perry: "The role of hydrogen sulphide in the control of breathing in hypoxic zebrafish (Danio rerio)." in: The Journal of physiology, Vol. 592, Issue 14, pp. 3075-88, (2014) (PubMed).

Dahlhoff, Worsch, Sailer, Hummel, Fiamoncini, Uebel, Obeid, Scherling, Geisel, Bader, Daniel: "Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels." in: Molecular metabolism, Vol. 3, Issue 5, pp. 565-80, (2014) (PubMed).

Fernandes, Ribeiro, Martínez, Orensanz, Barahona, Martínez-Sáenz, Recio, Benedito, Bustamante, Carballido, García-Sacristán, Prieto, Hernández: "Endogenous hydrogen sulfide has a powerful role in inhibitory neurotransmission to the pig bladder neck." in: The Journal of urology, Vol. 189, Issue 4, pp. 1567-73, (2013) (PubMed).

Markand, Tawfik, Ha, Gnana-Prakasam, Sonne, Ganapathy, Sen, Xian, Smith: "Cystathionine beta synthase expression in mouse retina." in: Current eye research, Vol. 38, Issue 5, pp. 597-604, (2013) (PubMed).

Dahlhoff, Desmarchelier, Sailer, Fürst, Haag, Ulbrich, Hummel, Obeid, Geisel, Bader, Daniel: "Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism." in: PLoS ONE, Vol. 8, Issue 3, pp. e57387, (2013) (PubMed).

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).
抗原

CBS (Cystathionine-beta-Synthase (CBS))

别名

CBS (CBS 产品)

别名

hip4 antibody, GB12529 antibody, CBS antibody, DDBDRAFT_0189727 antibody, DDBDRAFT_0191292 antibody, DDB_0189727 antibody, DDB_0191292 antibody, cbs antibody, AI047524 antibody, AI303044 antibody, HIP4 antibody, cb442 antibody, wu:fb37g05 antibody, wu:fm61c07 antibody, wu:fq06c06 antibody, zgc:113704 antibody, cystathionine-beta-synthase L homeolog antibody, cystathionine-beta-synthase antibody, cystathionine beta-synthase antibody, cystathionine beta-synthase CBS antibody, cystathionine beta synthase antibody, cystathionine-beta-synthase S homeolog antibody, cystathionine-beta-synthase b antibody, cbs.L antibody, cbs antibody, Cbs antibody, CBS antibody, CNA06170 antibody, Tb11.02.5400 antibody, cysB antibody, LOC100635325 antibody, cbs.S antibody, cbsb antibody

背景

CBS is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.The protein encoded by this gene is involved in the transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by this protein. CBS deficiency can cause homocystinuria which affects many organs and tissues, including the eyes and the skeletal, vascular and central nervous systems.
Alias Symbols: HIP4
Protein Interaction Partner: UBASH3A, UBE2I, PSMA1, PRKAG1, PIN1, EHHADH, CBS, SUMO1, UBC, NEDD8, PIAS3, RANBP9, PIAS1, CBX4, SRP14, RAD23B, PKM, NUCB1, IREB2, HSF1, LRSAM1, C14orf142, UBA5, IPO4, GOPC, PARP6, NPLOC4, DERA, ERO1L, DBNL, GPN1, PDLIM5, PLIN3, UBA2, GPSM1, COL4A3BP, UGP
Protein Size: 551

分子量

60 kDa

基因ID

875

NCBI登录号

NM_000071, NP_000062

UniProt

P35520