GRP78 抗体 (C-Term)
Quick Overview for GRP78 抗体 (C-Term) (ABIN7464913)
抗原
See all GRP78 (HSPA5) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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                                            抗原表位
- C-Term
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                                            特异性
- Knockdown/Knockout validation was supported by customer review data.
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            纯化方法
- Purified by antigen-affinity chromatography.
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                                            免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of mouse Grp78. The exact sequence is proprietary.
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                                            亚型
- IgG
 
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                                            应用备注
- WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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                                            说明
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                        Positive Control: Rat heart , Rat Lung , Rat Liver , Rat kidney , NIH-3T-3 , JC , BCL-1 , C2C12 , Raw264.7 , 293T , A431 , HeLa , HepG2 Validation: KO/KD, Orthogonal 
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 0.139 mg/mL
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                                            缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
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    - GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))
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                                            别名
- heat shock protein 5
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                                            背景
- Heat shock protein 5 , AL022860 , AU019543 , Bip , D2Wsu141e , D2Wsu17e , Grp78 , Hsce70 , SEZ-7 , Sez7 , baffled , mBiP,Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
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                                            分子量
- 72 kDa
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                                            基因ID
- 14828
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                                            UniProt
- P20029
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                                            途径
- Thyroid Hormone Synthesis, ER-Nucleus Signaling
 抗原
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