CIITA 抗体
Quick Overview for CIITA 抗体 (ABIN7464900)
抗原
See all CIITA 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human CIITA. The exact sequence is proprietary.
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亚型
- IgG
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anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 945-1130) antibody
CIITA 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (Internal Region) antibodyCIITA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (C-Term) antibodyCIITA 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 841-890) antibodyCIITA 适用: 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (C-Term) antibodyCIITA 适用: 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 1-333) antibodyCIITA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Class II, Major Histocompatibility Complex, Transactivator (CIITA) (AA 706-755) antibodyCIITA 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Raji , Raji NE
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.31 mg/mL
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缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- CIITA (Class II, Major Histocompatibility Complex, Transactivator (CIITA))
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别名
- class II major histocompatibility complex transactivator
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背景
- Class II major histocompatibility complex transactivator , C2TA , CIITAIV , MHC2TA , NLRA,This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the "master control factor" for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. [provided by RefSeq]
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分子量
- 124 kDa
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基因ID
- 4261
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UniProt
- P33076
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途径
- Cancer Immune Checkpoints
抗原
-
