OCT4 抗体
Quick Overview for OCT4 抗体 (ABIN7464858)
抗原
See all OCT4 (POU5F1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人
-
纯化方法
- Affinity purified by Protein G.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human Oct4. The exact sequence is proprietary.
-
亚型
- IgG1
-
-
-
-
应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: NT2D1 , OCT 3/4 transfected HeLa , human ESC
Validation: KO/KD, Overexpression
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, No Preservative
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
-
别名
- POU class 5 homeobox 1
-
背景
- POU class 5 homeobox 1 , OCT3 , OCT4 , OTF-3 , OTF3 , OTF4 , Oct-3 , Oct-4,This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]
-
分子量
- 39 kDa
-
基因ID
- 5460
-
UniProt
- Q01860
-
途径
- Stem Cell Maintenance
抗原
-