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SLC3A2 抗体 (AA 231-280)

Name: SLC3A2 抗体 (AA 231-280)
SKU: ABIN719546
Availability: OutOfStock

There are 2+ publications for this product available. The 兔多克隆 anti-SLC3A2 antibody is suitable to detect SLC3A2 in samples from 人, 大鼠和 Pig. It has been validated for WB, ELISA, IHC (p), IF (p), IF (cc) 和 IHC (fro).

Formalin-fixed and paraffin embedded rat colitis tissue labeled with Anti CD98 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (SLC3A2 抗体 (AA 231-280))

IHC (p)

Lane 1: rat brain lysates Lane 2: human colon carcinoma lysates probed with Anti CD98 Polyclonal Antibody, Unconjugated (ABIN719546) at 1:200 in 4 °C. (SLC3A2 抗体 (AA 231-280))

SDS

Formalin-fixed and paraffin embedded rat colitis tissue labeled with Anti CD98 Polyclonal Antibody, Unconjugated (ABIN719546) at 1:200 followed by conjugation to the secondary antibody and DAB staining (SLC3A2 抗体 (AA 231-280))

IHC

3 images

(2 references)

产品编号 ABIN719546

发货至: 中国

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Quick Overview for SLC3A2 抗体 (AA 231-280) (ABIN719546)

抗原

See all SLC3A2 抗体

SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

适用

人, 大鼠, Pig

宿主

兔

克隆类型

多克隆

标记

This SLC3A2 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product SLC3A2 Primary Antibody

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AA 231-280

交叉反应

人, Pig, 大鼠

预测反应

Mouse,Rabbit,Guinea Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CD98

亚型

IgG
anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 1-529) antibody
SLC3A2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody
SLC3A2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 360-529) antibody
SLC3A2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 150-164), (Extracellular) antibody
SLC3A2 适用: 小鼠 WB, FACS, IHC, LCI 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 213-349) antibody
SLC3A2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody (Biotin)
SLC3A2 适用: 人 FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-108 Biotin

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody (FITC)
SLC3A2 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-108 FITC

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 588-615), (C-Term) antibody
SLC3A2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22529 unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 285-521) antibody
SLC3A2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody
SLC3A2 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal H202-529-4-1-4 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Hutterer, Ebner, Riemenschneider, Willuweit, McCoy, Egger, Schröder, Wendl, Hellwig, Grosse, Menhart, Proescholdt, Fritsch, Urbach, Stockhammer, Roelcke, Galldiks, Meyer, Langen, Hau, Trinka: "Epileptic Activity Increases Cerebral Amino Acid Transport Assessed by 18F-Fluoroethyl-l-Tyrosine Amino Acid PET: A Potential Brain Tumor Mimic." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 58, Issue 1, pp. 129-137, (2016) (PubMed).

Qiu, Qin, Luo, Zhang, Sun, Jiao, Li, Yin: "Protein Restriction with Amino Acid-Balanced Diets Shrinks Circulating Pool Size of Amino Acid by Decreasing Expression of Specific Transporters in the Small Intestine." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162475, (2016) (PubMed).
抗原

SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

别名

CD98

背景

Synonyms: 4F2, CD98, MDU1, 4F2HC, 4T2HC, NACAE, CD98HC, 4F2 cell-surface antigen heavy chain, 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2, SLC3A2
Background: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.

基因ID

6520

UniProt

P08195