LIG1 抗体
Quick Overview for LIG1 抗体 (ABIN7464724)
抗原
See all LIG1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠
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纯化方法
- Protein G purified
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免疫原
- Full-length recombinant human DNA Ligase I protein
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Positive Control: MCF7
Validation: Recombinant antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.54 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))
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别名
- DNA ligase 1
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背景
- DNA ligase 1,This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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分子量
- 102 kDa
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基因ID
- 3978
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UniProt
- P18858
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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