MCM4 抗体 (C-Term)
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Quick Overview for MCM4 抗体 (C-Term) (ABIN7464669)
抗原
See all MCM4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- IP/MS validation was supported by references (PMID:30377397)
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交叉反应
- 人, 小鼠, 斑马鱼
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human MCM4. The exact sequence is proprietary.
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亚型
- IgG
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anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 1-863) antibody
MCM4 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 1-863) antibodyMCM4 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 2-141) antibodyMCM4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) antibodyMCM4 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) antibodyMCM4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2495 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Deficient 4 (MCM4) antibodyMCM4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4960 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 637-665) antibodyMCM4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 350-450) antibodyMCM4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) antibodyMCM4 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 267-366) antibodyMCM4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: Jurkat , Raji , NCI-H929 , Neuro 2A , C8D30 , NIH-3T3 , Raw264.7 , C2C12
Validation: IP/MS
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
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别名
- minichromosome maintenance complex component 4
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背景
- Minichromosome maintenance complex component 4 , CDC21 , CDC54 , IMD54 , NKCD , NKGCD , P1-CDC21 , hCdc21,The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]
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分子量
- 97 kDa
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基因ID
- 4173
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UniProt
- P33991
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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