MCM3 抗体
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北京 101111
Quick Overview for MCM3 抗体 (ABIN7464585)
抗原
See all MCM3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- IP/MS validation was supported by references (PMID:30377398)
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human MCM3. The exact sequence is proprietary.
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亚型
- IgG
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anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibody
MCM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibodyMCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibodyMCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 13-27), (N-Term) antibodyMCM3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibodyMCM3 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 IHC 宿主: 小鼠 Monoclonal 503M unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyKD Validated MCM3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2490 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2
Validation: IP/MS
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.71 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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别名
- minichromosome maintenance complex component 3
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背景
- Minichromosome maintenance complex component 3 , HCC5 , P1-MCM3 , P1.h , RLFB,The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq]
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分子量
- 91 kDa
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基因ID
- 4172
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UniProt
- P25205
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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