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ATF3 抗体

This anti-ATF3 antibody is a 兔 多克隆 antibody detecting ATF3 in WB, ICC 和 IF. Suitable for 人.
产品编号 ABIN7464434
发货至: 中国

Quick Overview for ATF3 抗体 (ABIN7464434)

抗原

See all ATF3 抗体
ATF3 (Activating Transcription Factor 3 (ATF3))

适用

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宿主

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克隆类型

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多克隆

标记

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This ATF3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

质量等级

KO Validated
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Full length human ATF3 Recombinant protein.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HCT116 (UVC-treated 10 J/m2 and recover for 8 hr) , HeLa

    Validation: KO/KD, Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ATF3 (Activating Transcription Factor 3 (ATF3))

    别名

    activating transcription factor 3

    背景

    Activating transcription factor 3,Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. [provided by RefSeq]

    分子量

    21 kDa

    基因ID

    467

    UniProt

    P18847

    途径

    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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