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TET1 抗体

This 小鼠 单克隆 anti-TET1 antibody (Clone GT465) specifically detects TET1 in WB, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7464383
发货至: 中国
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Quick Overview for TET1 抗体 (ABIN7464383)

抗原

See all TET1 抗体
TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))

适用

  • 16
  • 12
  • 4
  • 1

宿主

  • 15
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  • 1
小鼠

克隆类型

  • 15
  • 7
单克隆

标记

  • 18
  • 2
  • 1
  • 1
This TET1 antibody is un-conjugated

应用范围

  • 16
  • 10
  • 5
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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

GT465
  • 交叉反应

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: DDDDK-human TET1-transfected 293T cells , NT2D1 nuclear extract

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))

    别名

    tet methylcytosine dioxygenase 1

    背景

    Tet methylcytosine dioxygenase 1 , CXXC6 , LCX , bA119F7.1,Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.

    分子量

    235 kDa

    基因ID

    80312

    UniProt

    Q8NFU7

    途径

    Stem Cell Maintenance, Warburg Effect
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