TET1 抗体
Quick Overview for TET1 抗体 (ABIN7464383)
抗原
See all TET1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Affinity purified by Protein G.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.
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亚型
- IgG1
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anti-Tet Methylcytosine Dioxygenase 1 (TET1) (AA 2038-2136) antibody
TET1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-Tet Methylcytosine Dioxygenase 1 (TET1) (AA 1700-1800) antibodyTET1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 1 (TET1) (AA 1845-1879), (C-Term) antibodyTET1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52496 unconjugated
anti-Tet Methylcytosine Dioxygenase 1 (TET1) (C-Term) antibodyTET1 适用: 人, 小鼠 WB, IHC, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 1 (TET1) (C-Term) antibodyTET1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: DDDDK-human TET1-transfected 293T cells , NT2D1 nuclear extract
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, No Preservative
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))
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别名
- tet methylcytosine dioxygenase 1
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背景
- Tet methylcytosine dioxygenase 1 , CXXC6 , LCX , bA119F7.1,Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.
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分子量
- 235 kDa
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基因ID
- 80312
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UniProt
- Q8NFU7
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途径
- Stem Cell Maintenance, Warburg Effect
抗原
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