电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

TET1 抗体 (C-Term)

TET1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991985
发货至: 中国
  • 抗原 See all TET1 抗体
    TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 2030-2080, C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 14
    • 7
    • 1
    克隆类型
    • 13
    • 9
    多克隆
    标记
    • 18
    • 2
    • 1
    • 1
    This TET1 antibody is un-conjugated
    应用范围
    • 16
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    TET1 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with TET2 and TET3.
    纯化方法
    TET1 antibody is affinity chromatography purified via peptide column.
    免疫原
    TET1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TET1. The immunogen is located within amino acids 2030 - 2080 of TET1.
    亚型
    IgG
    Top Product
    Discover our top product TET1 Primary Antibody
  • 应用备注
    TET1 antibody can be used for detection of TET1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TET1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TET1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))
    别名
    TET1 (TET1 产品)
    别名
    CXXC6 antibody, LCX antibody, bA119F7.1 antibody, 2510010B09Rik antibody, AA517754 antibody, BB001228 antibody, Cxxc6 antibody, D10Ertd17e antibody, mKIAA1676 antibody, tet methylcytosine dioxygenase 1 antibody, solute carrier family 25 member 16 antibody, TET1 antibody, Tet1 antibody, SLC25A16 antibody
    背景
    TET1, a member of the ten-eleven-translocation (TET) family of genes, was initially discovered as a fusion partner of MLL in acute myeloid leukemias containing the t(10,11)(q22,q23) (1). It is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine (2). TET1 expression is regulated during inflammation in both THP-1 and primary dendritic cells, and is a negative transcriptional regulator of IL-1beta following and inflammatory stimulus (3). Recent evidence has shown that TET1 is part of a signaling pathway that regulates breast cancer growth and metastasis (4).
    分子量
    Predicted: 235 kDa

    Observed: 240 kDa
    基因ID
    80312
    NCBI登录号
    NP_085128
    UniProt
    Q8NFU7
    途径
    Stem Cell Maintenance, Warburg Effect
You are here:
客服