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ZYX 抗体 (N-Term)

This anti-ZYX antibody is a 兔 多克隆 antibody detecting ZYX in WB, IF 和 ICC. Suitable for 人.
产品编号 ABIN7464189
发货至: 中国

Quick Overview for ZYX 抗体 (N-Term) (ABIN7464189)

抗原

See all ZYX 抗体
ZYX (Zyxin (ZYX))

适用

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  • 1
  • 1
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宿主

  • 53
  • 11
  • 1

克隆类型

  • 48
  • 16
多克隆

标记

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This ZYX antibody is un-conjugated

应用范围

  • 44
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Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

质量等级

KO Validated
  • 抗原表位

    • 7
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    • 2
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    N-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Zyxin. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.46 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    ZYX (Zyxin (ZYX))

    别名

    zyxin

    背景

    Zyxin , ESP-2 , HED-2,Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq]

    分子量

    61 kDa

    基因ID

    7791

    UniProt

    Q15942
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