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MCM6 抗体 (C-Term)

This anti-MCM6 antibody is a 兔 多克隆 antibody detecting MCM6 in WB, IF, IHC (p), ICC, IP 和 ChIP. Suitable for 人.
产品编号 ABIN7464170
发货至: 中国

Quick Overview for MCM6 抗体 (C-Term) (ABIN7464170)

抗原

See all MCM6 抗体
MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

适用

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宿主

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克隆类型

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多克隆

标记

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This MCM6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)

质量等级

KO Validated
  • 抗原表位

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    C-Term

    特异性

    IP/MS validation was supported by references (PMID:30377417)

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human MCM6. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2

    Validation: IP/MS, KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

    别名

    minichromosome maintenance complex component 6

    背景

    Minichromosome maintenance complex component 6 , MCG40308 , Mis5 , P105MCM,The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. [provided by RefSeq]

    分子量

    93 kDa

    基因ID

    4175

    UniProt

    Q14566

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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