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PD-1 抗体

This anti-PD-1 antibody is a 大鼠 单克隆 antibody detecting PD-1 in FACS. Suitable for 小鼠.
产品编号 ABIN7457960
发货至: 中国

Quick Overview for PD-1 抗体 (ABIN7457960)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

  • 207
  • 91
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小鼠

宿主

  • 108
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  • 40
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  • 3
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  • 2
  • 1
  • 1
大鼠

克隆类型

  • 198
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  • 5
单克隆

标记

  • 147
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  • 1
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  • 1
  • 1
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This PD-1 antibody is un-conjugated

应用范围

  • 147
  • 109
  • 95
  • 59
  • 46
  • 32
  • 27
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Flow Cytometry (FACS)

克隆位点

29F-1A12
  • 纯化方法

    Purified

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Matching Isotype Control: Purified Rat IgG2a, κ Isotype Control (ABIN7469837)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    CD279/PD-1

    背景

    PD-1, Programmed Death-1,CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

    基因ID

    18566

    UniProt

    Q02242

    途径

    Cancer Immune Checkpoints
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