PD-1 抗体
Quick Overview for PD-1 抗体 (ABIN7457959)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified
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过滤
- 0.2 μm filtered
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内毒素水平
- Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
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亚型
- IgG2a, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Matching Isotype Control: AF/LE Purified Rat IgG2a, κ Isotype Control (ABIN7469836)
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C. Do not freeze.
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
- CD279/PD-1
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背景
- PD-1, Programmed Death-1,CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
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基因ID
- 18566
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UniProt
- Q02242
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途径
- Cancer Immune Checkpoints
抗原
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