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CD8 抗体

This anti-CD8 antibody is a 小鼠 单克隆 antibody detecting CD8 in FACS 和 Dep. Suitable for 人.
产品编号 ABIN7457939
发货至: 中国

Quick Overview for CD8 抗体 (ABIN7457939)

抗原

See all CD8 抗体
CD8

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Depletion (Dep)

克隆位点

OKT-8
  • 纯化方法

    Purified

    过滤

    0.2 μm filtered

    内毒素水平

    Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Matching Isotype Control: AF/LE Purified Mouse IgG2a, κ Isotype Control (ABIN7469784)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    CD8

    别名

    CD8

    背景

    T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL,CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

    基因ID

    925

    UniProt

    P01732
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