CD8 抗体
Quick Overview for CD8 抗体 (ABIN7457939)
抗原
See all CD8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Purified
-
过滤
- 0.2 μm filtered
-
内毒素水平
- Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
-
亚型
- IgG2a, kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
Matching Isotype Control: AF/LE Purified Mouse IgG2a, κ Isotype Control (ABIN7469784)
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)
-
储存液
- Azide free
-
储存条件
- 4 °C
-
储存方法
- Store at 2~8°C. Do not freeze.
-
-
- CD8
-
别名
- CD8
-
背景
- T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL,CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
-
基因ID
- 925
-
UniProt
- P01732
抗原
-