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CD80 抗体

This anti-CD80 antibody is a Armenian Hamster 单克隆 antibody detecting CD80 in FACS 和 BR. Suitable for 小鼠.
产品编号 ABIN7457845
发货至: 中国

Quick Overview for CD80 抗体 (ABIN7457845)

抗原

See all CD80 抗体
CD80

适用

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小鼠

宿主

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Armenian Hamster

克隆类型

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单克隆

标记

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This CD80 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Blocking Reagent (BR)

克隆位点

16-10A1
  • 纯化方法

    Purified

    过滤

    0.2 μm filtered

    内毒素水平

    Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Matching Isotype Control: AF/LE Purified Armenian Hamster IgG Isotype Control (ABIN7469872)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

    储存液

    Azide free

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    CD80

    别名

    CD80

    背景

    T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7,CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

    基因ID

    12519

    UniProt

    Q00609

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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