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SELPLG 抗体 (PerCP-Cy5.5)

This anti-SELPLG antibody is a 大鼠 单克隆 antibody detecting SELPLG in FACS. Suitable for 小鼠.
产品编号 ABIN7457731
发货至: 中国

Quick Overview for SELPLG 抗体 (PerCP-Cy5.5) (ABIN7457731)

抗原

See all SELPLG 抗体
SELPLG (Selectin P Ligand (SELPLG))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This SELPLG antibody is conjugated to PerCP-Cy5.5

应用范围

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Flow Cytometry (FACS)

克隆位点

4RA10
  • 亚型

    IgG1, kappa
  • 应用备注

    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

    说明

    Matching Isotype Control: PerCP/Cyanine5.5 Rat IgG1, κ Isotype Control (ABIN7469827)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    SELPLG (Selectin P Ligand (SELPLG))

    别名

    CD162

    背景

    P-selectin glycoprotein ligand 1,Selplg,PSGL-1,Selectin P ligand,CD162,The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.

    基因ID

    20345

    UniProt

    Q62170
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