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PD-1 抗体 (PE-Cy7)

This PE-Cy7-conjugated 大鼠 单克隆 anti-PD-1 antibody (Clone 29F-1A12) specifically detects PD-1 in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7457575
发货至: 中国
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北京 101111
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Quick Overview for PD-1 抗体 (PE-Cy7) (ABIN7457575)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This PD-1 antibody is conjugated to PE-Cy7

应用范围

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Flow Cytometry (FACS)

克隆位点

29F-1A12
  • 亚型

    IgG2a, kappa
  • 应用备注

    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

    说明

    Matching Isotype Control: PE/Cyanine7 Rat IgG2a, κ Isotype Control (ABIN7469844)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    CD279/PD-1

    背景

    PD-1, Programmed Death-1,CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

    基因ID

    18566

    UniProt

    Q02242

    途径

    Cancer Immune Checkpoints
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