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ITGA4 抗体 (PE-Cy5.5)

This anti-ITGA4 antibody is a 小鼠 单克隆 antibody detecting ITGA4 in FACS. Suitable for 人.
产品编号 ABIN7457432
发货至: 中国

Quick Overview for ITGA4 抗体 (PE-Cy5.5) (ABIN7457432)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGA4 antibody is conjugated to PE-Cy5.5

应用范围

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Flow Cytometry (FACS)

克隆位点

9F10
  • 亚型

    IgG1, kappa
  • 应用备注

    The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    说明

    Matching Isotype Control: PE/Cyanine5.5 Mouse IgG1, κ Isotype Control (ABIN7469765)

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    CD49d

    背景

    Integrin alpha-4,CD49 antigen-like family member D,Integrin alpha-IV,VLA-4 subunit alpha,CD49d,ITGA4,CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

    基因ID

    3676

    UniProt

    P13612

    途径

    Integrin Complex
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