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CD28 抗体 (PE-Cy5)

The 小鼠 单克隆 anti-CD28 antibody is suitable to detect CD28 in samples from 人. It has been validated for FACS.
产品编号 ABIN7457323
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD28 抗体 (PE-Cy5) (ABIN7457323)

抗原

See all CD28 抗体
CD28

适用

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小鼠

克隆类型

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单克隆

标记

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This CD28 antibody is conjugated to PE-Cy5

应用范围

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Flow Cytometry (FACS)

克隆位点

CD28-2
  • 亚型

    IgG1, kappa
  • 应用备注

    The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    说明

    Matching Isotype Control: PE/Cyanine5 Mouse IgG1, κ Isotype Control

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    CD28

    别名

    CD28

    背景

    PAS2,MNS,HGpMiX,GYPA,GPSAT,CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

    基因ID

    940

    UniProt

    P10747

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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