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LAMP1 抗体 (PE)

This anti-LAMP1 antibody is a 小鼠 单克隆 antibody detecting LAMP1 in FACS. Suitable for 人.
产品编号 ABIN7457085
发货至: 中国

Quick Overview for LAMP1 抗体 (PE) (ABIN7457085)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This LAMP1 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

H4A3
  • 亚型

    IgG1, kappa
  • 应用备注

    The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    说明

    Matching Isotype Control: PE Mouse IgG1, κ Isotype Control (ABIN7469761)

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    CD107a/LAMP-1

    背景

    Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1,CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

    基因ID

    3916

    UniProt

    P11279

    途径

    Autophagy
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