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IL2 Receptor beta 抗体 (PE)

This PE-conjugated 大鼠 单克隆 anti-IL2 Receptor beta antibody (Clone 5H4) specifically detects IL2 Receptor beta in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7456974
发货至: 中国
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Quick Overview for IL2 Receptor beta 抗体 (PE) (ABIN7456974)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

  • 106
  • 90
  • 18
  • 5
  • 1
小鼠

宿主

  • 80
  • 39
  • 37
  • 1
大鼠

克隆类型

  • 79
  • 76
  • 2
单克隆

标记

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  • 1
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This IL2 Receptor beta antibody is conjugated to PE

应用范围

  • 83
  • 71
  • 31
  • 26
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  • 17
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  • 8
  • 8
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Flow Cytometry (FACS)

克隆位点

5H4
  • 亚型

    IgG2a, kappa
  • 应用备注

    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

    说明

    Matching Isotype Control: PE Rat IgG2a, κ Isotype Control (ABIN7469840)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    CD122

    背景

    Interleukin-2 receptor subunit beta,Il2rb,IL-2 receptor subunit beta, IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122,CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.

    基因ID

    16185

    UniProt

    P16297

    途径

    JAK/STAT Signaling, Growth Factor Binding
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