IL2 Receptor beta 抗体 (PE)
Quick Overview for IL2 Receptor beta 抗体 (PE) (ABIN7456974)
抗原
See all IL2 Receptor beta (IL2RB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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亚型
- IgG2a, kappa
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应用备注
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
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说明
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Matching Isotype Control: PE Rat IgG2a, κ Isotype Control (ABIN7469840)
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.05 % Proclin300, 1 % BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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别名
- CD122
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背景
- Interleukin-2 receptor subunit beta,Il2rb,IL-2 receptor subunit beta, IL-2R subunit beta,IL-2RB,High affinity IL-2 receptor subunit beta,p70-75,CD122,CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
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基因ID
- 16185
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UniProt
- P16297
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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