PD-1 抗体 (FITC)
Quick Overview for PD-1 抗体 (FITC) (ABIN7456906)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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亚型
- IgG1, kappa
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应用备注
- The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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说明
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Matching Isotype Control: FITC Mouse IgG1, κ Isotype Control (ABIN7469760)
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限制
- 仅限研究用
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缓冲液
- PBS with 0.05 % Proclin300, 1 % BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
- CD279/PD-1
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背景
- PDCD1,PD1,Protein PD-1,hPD-1,Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
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基因ID
- 5133
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UniProt
- Q15116
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途径
- Cancer Immune Checkpoints
抗原
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