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IL7R 抗体 (Biotin)

The Biotin-conjugated 小鼠 单克隆 anti-IL7R antibody (Clone A019D5) (ABIN7456688) specifically detects IL7R in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN7456688
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for IL7R 抗体 (Biotin) (ABIN7456688)

抗原

See all IL7R 抗体
IL7R (Interleukin 7 Receptor (IL7R))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL7R antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

A019D5
  • 亚型

    IgG1, kappa
  • 应用备注

    For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

    说明

    Matching Isotype Control: Biotin Mouse Rat IgG1, κ Isotype Control (ABIN7469769)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    IL7R (Interleukin 7 Receptor (IL7R))

    别名

    CD127/IL-7RA

    背景

    Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7Rα,CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

    基因ID

    3575

    UniProt

    P16871

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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