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CD80 抗体 (Biotin)

This Biotin-conjugated Armenian Hamster 单克隆 anti-CD80 antibody (Clone 16-10A1) specifically detects CD80 in FACS. The antibody is reactive with 小鼠 samples.
产品编号 ABIN7456616
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for CD80 抗体 (Biotin) (ABIN7456616)

抗原

See all CD80 抗体
CD80

适用

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小鼠

宿主

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Armenian Hamster

克隆类型

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单克隆

标记

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This CD80 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

16-10A1
  • 亚型

    IgG
  • 应用备注

    For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

    说明

    Matching Isotype Control: Biotin Armenian Hamster IgG Isotype Control (ABIN7469874)

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C. Do not freeze.
  • 抗原

    CD80

    别名

    CD80

    背景

    T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7,CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

    基因ID

    12519

    UniProt

    Q00609

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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