CD163 抗体 (APC)
Quick Overview for CD163 抗体 (APC) (ABIN7456603)
抗原
See all CD163 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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亚型
- IgG2a, kappa
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应用备注
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
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说明
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Matching Isotype Control: APC Rat IgG2a, κ Isotype Control[2A3] (ABIN7469841)
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.05 % Proclin300, 1 % Protein protectant
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- CD163
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别名
- CD163
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背景
- M130, MM130, SCARI1,CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
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基因ID
- 93671
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UniProt
- Q2VLH6
抗原
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