Endoglin 抗体 (APC)
Quick Overview for Endoglin 抗体 (APC) (ABIN7456580)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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亚型
- IgG2a, kappa
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应用备注
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
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说明
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Matching Isotype Control: APC Rat IgG2a, κ Isotype Control (ABIN7469841)
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.05 % Proclin300, 1 % BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Endoglin (ENG)
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别名
- CD105
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背景
- Endoglin,END,Eng,CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
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基因ID
- 13805
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UniProt
- Q63961
抗原
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