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Endoglin 抗体 (APC)

This anti-Endoglin antibody is a 大鼠 单克隆 antibody detecting Endoglin in FACS. Suitable for 小鼠.
产品编号 ABIN7456580
发货至: 中国

Quick Overview for Endoglin 抗体 (APC) (ABIN7456580)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Endoglin antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

MJ7-18
  • 亚型

    IgG2a, kappa
  • 应用备注

    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

    说明

    Matching Isotype Control: APC Rat IgG2a, κ Isotype Control (ABIN7469841)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    Endoglin (ENG)

    别名

    CD105

    背景

    Endoglin,END,Eng,CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.

    基因ID

    13805

    UniProt

    Q63961
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