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IL-21 抗体 (APC)

This anti-IL-21 antibody is a 小鼠 单克隆 antibody detecting IL-21 in ICFC. Suitable for 人.
产品编号 ABIN7456559
发货至: 中国

Quick Overview for IL-21 抗体 (APC) (ABIN7456559)

抗原

See all IL-21 (IL21) 抗体
IL-21 (IL21) (Interleukin 21 (IL21))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-21 antibody is conjugated to APC

应用范围

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Intracellular Flow Cytometry (ICFC)

克隆位点

3A3-N2
  • 亚型

    IgG1, kappa
  • 应用备注

    The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

    说明

    Matching Isotype Control: APC Mouse IgG1, κ Isotype Control (ABIN7469762)

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL-21

    背景

    Interleukin-21,IL-21,Za11,Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

    基因ID

    59067

    UniProt

    Q9HBE4

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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