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Complement Factor B 抗体

This anti-Complement Factor B antibody (ABIN7490606) is a Rabbit Chimeric antibody detecting Complement Factor B in FACS. Suitable for Human.
产品编号 ABIN7490606
发货至: 中国

Quick Overview for Complement Factor B 抗体 (ABIN7490606)

抗原

See all Complement Factor B (CFB) 抗体
Complement Factor B (CFB)

片段

Fc fragment

适用

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宿主

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克隆类型

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Chimeric

标记

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This Complement Factor B antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)
  • 产品特性

    Rabbit/Human Fc chimeric IgG1

    纯化方法

    Purified from cell culture supernatant by affinity chromatography

    亚型

    IgG1
  • 应用备注

    Flow Cyt  1:100

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    Complement Factor B (CFB)

    别名

    CFB

    背景

    AHUS4, ARMD14, BF, BFD, CFAB, CFBD, FB, FBI12, GBG, H2-Bf, PBF2
    Description: This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

    UniProt

    P00751

    途径

    Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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