IL4 Receptor 抗体
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北京 101111
Quick Overview for IL4 Receptor 抗体 (ABIN7490587)
抗原
See all IL4 Receptor (IL4R) 抗体片段
适用
宿主
克隆类型
标记
应用范围
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产品特性
- Rabbit/Human Fc chimeric IgG1
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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亚型
- IgG1
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应用备注
- Flow Cyt 1:100
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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别名
- IL4RA
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背景
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CD124, IL-4RA, IL4RA,
Description: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. -
UniProt
- P24394
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
抗原
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