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Recombinant FOXP3 抗体 (AA 275-325)

This anti-FOXP3 antibody is a 兔 单克隆 antibody detecting FOXP3 in WB, IP, ICC, IF (p), IHC (fp) 和 mIF. Suitable for 人.
产品编号 ABIN7455209
发货至: 中国

Quick Overview for Recombinant FOXP3 抗体 (AA 275-325) (ABIN7455209)

抗原

See all FOXP3 抗体
FOXP3 (Forkhead Box P3 (FOXP3))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This FOXP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Multiplex Immunofluorescence (mIF)

克隆位点

BLR034F
  • 抗原表位

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    AA 275-325

    原理

    Rabbit anti-FOXP3 Recombinant Monoclonal Antibody [BLR034F]

    免疫原

    between AA 275 and 325

    亚型

    IgG
  • 应用备注

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 20 µL/mg lysate

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 17:40:00

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    FOXP3 (Forkhead Box P3 (FOXP3))

    别名

    FOXP3

    背景

    Background: FOXP3 is a transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). It plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. FOXP3 can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases.  [taken from the Universal Protein Resource (UniProt) Q9BZS1].

    基因ID

    50943

    NCBI登录号

    NP_054728

    UniProt

    Q9BZS1

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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